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Agent Skills Guide

differential-tad-analysis

published 2026/01/23

This skill performs differential topologically associating domain (TAD) analysis using HiCExplorer's hicDifferentialTAD tool. It compares Hi-C contact matrices between two conditions based on existing TAD definitions to identify significantly altered chromatin domains.

📦 Install Skill

Command line install

Install directly with the `skills` CLI.

npx skills add BIsnake2001/ChromSkills/20_toolBased.differential-tad-analysis

Local download

Download only this skill directory.

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